Nicotinamide adenine dinucleotide, a coenzyme critical for cellular energy metabolism that declines with age. NAD+ precursors like NMN and NR are studied as longevity interventions.

Mechanistic target of rapamycin, a key nutrient-sensing pathway that regulates cell growth and aging. Inhibiting mTOR (e.g., with rapamycin) has shown lifespan extension in multiple organisms.

A class of drugs that selectively eliminate senescent (aged, dysfunctional) cells to reduce inflammation and improve tissue function.

What is Epigenetic clock?

A biomarker based on DNA methylation patterns that estimates biological age, often more predictive of health outcomes than chronological age.

The period of life spent in good health, free from chronic diseases and disability associated with aging.

An immunosuppressant drug that inhibits the mTOR pathway. Research shows rapamycin may extend lifespan and improve age-related health outcomes in multiple species.

What is Biological age?

A measure of how well or poorly your body is functioning relative to your chronological age, assessed through biomarkers such as DNA methylation, telomere length, and blood panels.

What is Caloric restriction?

A dietary regimen that reduces calorie intake without malnutrition. Caloric restriction is one of the most studied interventions shown to extend lifespan across species.

Protective caps at the ends of chromosomes that shorten with each cell division. Telomere length is associated with aging and age-related diseases.

A state in which cells permanently stop dividing but resist death, accumulating with age and secreting inflammatory factors that damage surrounding tissue.

A second-generation epigenetic clock that predicts time to death and is considered one of the most accurate measures of biological aging.

What is Inflammaging?

Chronic, low-grade inflammation that increases with age and contributes to the development of age-related diseases including cardiovascular disease, diabetes, and neurodegeneration.

The large-scale study of proteins in biological systems. In longevity research, proteomics identifies blood protein signatures that predict biological age and disease risk.

What is Yamanaka factors?

A set of four transcription factors (Oct4, Sox2, Klf4, c-Myc) that can reprogram adult cells to a pluripotent state. Partial reprogramming with Yamanaka factors is being explored to reverse cellular aging.

Nicotinamide mononucleotide, a precursor to NAD+ that is widely studied as a supplement to boost cellular energy and combat age-related decline.

A gene-editing technology that allows precise modifications to DNA. In longevity research, CRISPR is used to study and potentially modify genes associated with aging.

Team Elles and Jelenew Partner to Drive Women’s Cycling Community in Loire Atlantique

On March 28, 2026, Team Elles, a French developmental cycling team, collaborated with high-performance cycling apparel brand JELENEW to host a Rando Ride in the Loire Atlantique region. This event, coinciding with the French Cup race weekend, attracted nearly 200 female cyclists, ranging from amateurs to seasoned competitors, underscoring a commitment to inclusivity and growth within the sport.

The Rando Ride served as a strategic engagement platform for JELENEW, which provided high-performance cycling gear and branded kits to participants. This initiative not only showcased the brand’s dedication to supporting female athletes but also highlighted the integration of advanced technical engineering with the evolving lifestyle of modern cycling. The collaboration aligns with Team Elles’ mission to lower barriers for women and youth in cycling, following their successful 2024 season where they achieved top amateur rankings.

The key takeaway from this partnership is the potential shift in the cycling apparel market towards more inclusive designs tailored specifically for women. By prioritizing female-specific technical apparel, JELENEW and Team Elles are setting a precedent that could influence future product development and marketing strategies in the cycling industry. This focus on inclusivity may catalyze broader initiatives aimed at empowering women in sports, ultimately fostering a more diverse and robust cycling community.

Source: globenewswire.com