Nicotinamide adenine dinucleotide, a coenzyme critical for cellular energy metabolism that declines with age. NAD+ precursors like NMN and NR are studied as longevity interventions.

Mechanistic target of rapamycin, a key nutrient-sensing pathway that regulates cell growth and aging. Inhibiting mTOR (e.g., with rapamycin) has shown lifespan extension in multiple organisms.

A class of drugs that selectively eliminate senescent (aged, dysfunctional) cells to reduce inflammation and improve tissue function.

What is Epigenetic clock?

A biomarker based on DNA methylation patterns that estimates biological age, often more predictive of health outcomes than chronological age.

The period of life spent in good health, free from chronic diseases and disability associated with aging.

An immunosuppressant drug that inhibits the mTOR pathway. Research shows rapamycin may extend lifespan and improve age-related health outcomes in multiple species.

What is Biological age?

A measure of how well or poorly your body is functioning relative to your chronological age, assessed through biomarkers such as DNA methylation, telomere length, and blood panels.

What is Caloric restriction?

A dietary regimen that reduces calorie intake without malnutrition. Caloric restriction is one of the most studied interventions shown to extend lifespan across species.

Protective caps at the ends of chromosomes that shorten with each cell division. Telomere length is associated with aging and age-related diseases.

A state in which cells permanently stop dividing but resist death, accumulating with age and secreting inflammatory factors that damage surrounding tissue.

A second-generation epigenetic clock that predicts time to death and is considered one of the most accurate measures of biological aging.

What is Inflammaging?

Chronic, low-grade inflammation that increases with age and contributes to the development of age-related diseases including cardiovascular disease, diabetes, and neurodegeneration.

The large-scale study of proteins in biological systems. In longevity research, proteomics identifies blood protein signatures that predict biological age and disease risk.

What is Yamanaka factors?

A set of four transcription factors (Oct4, Sox2, Klf4, c-Myc) that can reprogram adult cells to a pluripotent state. Partial reprogramming with Yamanaka factors is being explored to reverse cellular aging.

Nicotinamide mononucleotide, a precursor to NAD+ that is widely studied as a supplement to boost cellular energy and combat age-related decline.

A gene-editing technology that allows precise modifications to DNA. In longevity research, CRISPR is used to study and potentially modify genes associated with aging.

C3 Davos of Healthcare™ Silicon Valley Summit Tem Início Amanhã em Sunnyvale com a Presença do KFSH

A pivotal event in health innovation, the C3 Davos of Healthcare™ Silicon Valley Summit, is set to commence on April 27, 2026, at the Plug and Play Tech Center in Sunnyvale, California. This summit, themed “Healthtech Frontiers: Building The Health Ecosystem of Tomorrow,” is driven by a strategic partnership with the King Faisal Specialist Hospital & Research Centre (KFSH). Notable speakers include Dr. Björn Zoëga, who will discuss the transition from isolated digital pilots to integrated operational models in large hospital systems, and Dr. Petros Kotsidis, focusing on the future of AI in healthcare.

The summit’s significance lies in its exploration of how advancements in AI, biotechnology, and data can foster resilient, secure, and scalable health systems globally. Key discussions will cover AI-driven diagnostics, predictive medicine, advanced oncology, next-generation therapeutics, and the regulatory alignment necessary for international collaboration. The presence of influential figures, such as former U.S. Secretary of Defense Leon Panetta, underscores the strategic importance of health innovation in relation to economic competitiveness and national security.

A critical takeaway from this summit is the potential shift in how health systems approach digital transformation. By emphasizing integrated operational models and the role of AI, this event could catalyze a re-evaluation of current research paradigms and therapeutic development timelines. The insights gained may accelerate the adoption of innovative health technologies, ultimately enhancing patient outcomes and shaping the future landscape of healthcare delivery.

Source: globenewswire.com