Researchers found that a popular treatment known as dasatinib and quercetin (D+Q), which targets aging cells, may cause brain damage in mice. This combination, often used to improve health and longevity by clearing out senescent cells, showed effects similar to multiple sclerosis (MS) in the study. Specifically, D+Q treatment led to reduced myelination in the brain, which is crucial for neuron function, raising concerns about its safety for brain health.

This finding is significant for anyone interested in aging well. If you’re considering senolytic treatments like D+Q to enhance your healthspan, this research suggests that they could have unintended consequences. The study indicates that while D+Q might help with certain age-related conditions, it may also harm your brain’s ability to maintain healthy nerve function. This is particularly relevant for older adults, who are already at a higher risk for neurodegenerative diseases.

The research was conducted on aged mice, and while it provides valuable insights, it is still in an early stage. The effects observed in mice may not directly translate to humans, but the study highlights the need for caution. D+Q has been previously shown to have benefits in extending life in mice, but this new evidence suggests potential risks that warrant further investigation.

If you’re exploring ways to support healthy aging, it’s wise to stay informed about the treatments you consider. Always consult with a healthcare professional before starting any new supplement or treatment, especially those targeting aging or longevity.

Source: lifespan.io