Nicotinamide adenine dinucleotide, a coenzyme critical for cellular energy metabolism that declines with age. NAD+ precursors like NMN and NR are studied as longevity interventions.

Mechanistic target of rapamycin, a key nutrient-sensing pathway that regulates cell growth and aging. Inhibiting mTOR (e.g., with rapamycin) has shown lifespan extension in multiple organisms.

A class of drugs that selectively eliminate senescent (aged, dysfunctional) cells to reduce inflammation and improve tissue function.

What is Epigenetic clock?

A biomarker based on DNA methylation patterns that estimates biological age, often more predictive of health outcomes than chronological age.

The period of life spent in good health, free from chronic diseases and disability associated with aging.

An immunosuppressant drug that inhibits the mTOR pathway. Research shows rapamycin may extend lifespan and improve age-related health outcomes in multiple species.

What is Biological age?

A measure of how well or poorly your body is functioning relative to your chronological age, assessed through biomarkers such as DNA methylation, telomere length, and blood panels.

What is Caloric restriction?

A dietary regimen that reduces calorie intake without malnutrition. Caloric restriction is one of the most studied interventions shown to extend lifespan across species.

Protective caps at the ends of chromosomes that shorten with each cell division. Telomere length is associated with aging and age-related diseases.

A state in which cells permanently stop dividing but resist death, accumulating with age and secreting inflammatory factors that damage surrounding tissue.

A second-generation epigenetic clock that predicts time to death and is considered one of the most accurate measures of biological aging.

What is Inflammaging?

Chronic, low-grade inflammation that increases with age and contributes to the development of age-related diseases including cardiovascular disease, diabetes, and neurodegeneration.

The large-scale study of proteins in biological systems. In longevity research, proteomics identifies blood protein signatures that predict biological age and disease risk.

What is Yamanaka factors?

A set of four transcription factors (Oct4, Sox2, Klf4, c-Myc) that can reprogram adult cells to a pluripotent state. Partial reprogramming with Yamanaka factors is being explored to reverse cellular aging.

Nicotinamide mononucleotide, a precursor to NAD+ that is widely studied as a supplement to boost cellular energy and combat age-related decline.

A gene-editing technology that allows precise modifications to DNA. In longevity research, CRISPR is used to study and potentially modify genes associated with aging.

A cellular housekeeping process where cells break down and recycle damaged components. Declines with age and is stimulated by fasting.

What is Intermittent fasting?

An eating pattern that cycles between periods of fasting and eating. Various protocols (16:8, 5:2) are studied for metabolic, cardiovascular, and longevity benefits.

What is Zone 2 cardio?

Low-intensity aerobic exercise performed at roughly 60–70% of maximum heart rate, primarily using the aerobic energy system. Associated with mitochondrial health and longevity.

Geographic regions identified by researchers where people consistently live longer and healthier lives than average, including Sardinia, Okinawa, and Loma Linda.

Could new T cell therapies improve cancer treatment outcomes?

Researchers at IN8bio are making strides in cancer treatment with their innovative gamma-delta (γδ) T cell therapies. These therapies are designed to target tough cancers like glioblastoma, a particularly aggressive brain tumor. IN8bio is set to present new clinical data at major medical conferences in May and June 2026, including the American Society of Clinical Oncology (ASCO) Annual Meeting. This could be significant news for people facing difficult-to-treat cancers, as the data may reveal survival benefits for patients treated with their novel therapies.

For individuals concerned about cancer and looking for effective treatments, this research could offer hope. The γδ T cells have unique properties that allow them to differentiate between healthy and diseased tissues. This means they could potentially improve outcomes for patients with challenging cancers, making it easier for doctors to target and treat these diseases. The upcoming presentations will provide more insights into how these therapies could change the landscape of cancer treatment and enhance survival rates.

Currently, the research is in the clinical trial phase, with presentations scheduled to share findings on the effectiveness of these therapies. While the results are promising, they are not yet proven on a large scale, so it’s important to stay informed about future developments. As IN8bio continues to advance its research, the hope is that these therapies will become a viable option for patients battling aggressive cancers.

For those interested in staying updated, following IN8bio’s presentations at the upcoming conferences may provide valuable insights into new treatment options and advancements in cancer care.

Source: globenewswire.com