Nicotinamide adenine dinucleotide, a coenzyme critical for cellular energy metabolism that declines with age. NAD+ precursors like NMN and NR are studied as longevity interventions.

Mechanistic target of rapamycin, a key nutrient-sensing pathway that regulates cell growth and aging. Inhibiting mTOR (e.g., with rapamycin) has shown lifespan extension in multiple organisms.

A class of drugs that selectively eliminate senescent (aged, dysfunctional) cells to reduce inflammation and improve tissue function.

What is Epigenetic clock?

A biomarker based on DNA methylation patterns that estimates biological age, often more predictive of health outcomes than chronological age.

The period of life spent in good health, free from chronic diseases and disability associated with aging.

An immunosuppressant drug that inhibits the mTOR pathway. Research shows rapamycin may extend lifespan and improve age-related health outcomes in multiple species.

What is Biological age?

A measure of how well or poorly your body is functioning relative to your chronological age, assessed through biomarkers such as DNA methylation, telomere length, and blood panels.

What is Caloric restriction?

A dietary regimen that reduces calorie intake without malnutrition. Caloric restriction is one of the most studied interventions shown to extend lifespan across species.

Protective caps at the ends of chromosomes that shorten with each cell division. Telomere length is associated with aging and age-related diseases.

A state in which cells permanently stop dividing but resist death, accumulating with age and secreting inflammatory factors that damage surrounding tissue.

A second-generation epigenetic clock that predicts time to death and is considered one of the most accurate measures of biological aging.

What is Inflammaging?

Chronic, low-grade inflammation that increases with age and contributes to the development of age-related diseases including cardiovascular disease, diabetes, and neurodegeneration.

The large-scale study of proteins in biological systems. In longevity research, proteomics identifies blood protein signatures that predict biological age and disease risk.

What is Yamanaka factors?

A set of four transcription factors (Oct4, Sox2, Klf4, c-Myc) that can reprogram adult cells to a pluripotent state. Partial reprogramming with Yamanaka factors is being explored to reverse cellular aging.

Nicotinamide mononucleotide, a precursor to NAD+ that is widely studied as a supplement to boost cellular energy and combat age-related decline.

A gene-editing technology that allows precise modifications to DNA. In longevity research, CRISPR is used to study and potentially modify genes associated with aging.

A cellular housekeeping process where cells break down and recycle damaged components. Declines with age and is stimulated by fasting.

What is Intermittent fasting?

An eating pattern that cycles between periods of fasting and eating. Various protocols (16:8, 5:2) are studied for metabolic, cardiovascular, and longevity benefits.

What is Zone 2 cardio?

Low-intensity aerobic exercise performed at roughly 60–70% of maximum heart rate, primarily using the aerobic energy system. Associated with mitochondrial health and longevity.

Geographic regions identified by researchers where people consistently live longer and healthier lives than average, including Sardinia, Okinawa, and Loma Linda.

How new tech is changing disease diagnosis and treatment

Researchers found that Proscia®, a company focused on enhancing pathology in precision medicine, has won the MedTech Breakthrough Award for the second year in a row. This recognition highlights how Proscia’s technology is helping pharmaceutical companies leverage real-time pathology data to develop more effective therapies. By using their Concentriq® platform, Proscia connects major pharmaceutical firms and laboratories to analyze tissue images and clinical records, enabling quicker and more accurate diagnoses.

This advancement is significant for anyone interested in healthy aging and longevity. The ability to analyze pathology data in real time could lead to the development of more personalized treatments, which may improve outcomes for various health conditions. For example, if you or a loved one is dealing with a serious illness, this technology could help identify the most effective treatment options more swiftly, potentially enhancing recovery and overall well-being.

The research behind Proscia’s technology is grounded in its partnerships with 16 of the top 20 pharmaceutical companies, making it a leader in the field. While the MedTech Breakthrough Award is a strong endorsement of Proscia’s impact, it’s important to note that this is not a clinical trial or a direct study of health outcomes. Instead, it reflects the company’s role in improving the drug development process, which could eventually benefit patients.

As this technology continues to evolve, staying informed about advancements in precision medicine can help you understand how new treatments may become available. Engaging with your healthcare provider about these developments may also empower you to make informed decisions about your health.

Source: globenewswire.com