Nicotinamide adenine dinucleotide, a coenzyme critical for cellular energy metabolism that declines with age. NAD+ precursors like NMN and NR are studied as longevity interventions.

Mechanistic target of rapamycin, a key nutrient-sensing pathway that regulates cell growth and aging. Inhibiting mTOR (e.g., with rapamycin) has shown lifespan extension in multiple organisms.

A class of drugs that selectively eliminate senescent (aged, dysfunctional) cells to reduce inflammation and improve tissue function.

What is Epigenetic clock?

A biomarker based on DNA methylation patterns that estimates biological age, often more predictive of health outcomes than chronological age.

The period of life spent in good health, free from chronic diseases and disability associated with aging.

An immunosuppressant drug that inhibits the mTOR pathway. Research shows rapamycin may extend lifespan and improve age-related health outcomes in multiple species.

What is Biological age?

A measure of how well or poorly your body is functioning relative to your chronological age, assessed through biomarkers such as DNA methylation, telomere length, and blood panels.

What is Caloric restriction?

A dietary regimen that reduces calorie intake without malnutrition. Caloric restriction is one of the most studied interventions shown to extend lifespan across species.

Protective caps at the ends of chromosomes that shorten with each cell division. Telomere length is associated with aging and age-related diseases.

A state in which cells permanently stop dividing but resist death, accumulating with age and secreting inflammatory factors that damage surrounding tissue.

A second-generation epigenetic clock that predicts time to death and is considered one of the most accurate measures of biological aging.

What is Inflammaging?

Chronic, low-grade inflammation that increases with age and contributes to the development of age-related diseases including cardiovascular disease, diabetes, and neurodegeneration.

The large-scale study of proteins in biological systems. In longevity research, proteomics identifies blood protein signatures that predict biological age and disease risk.

What is Yamanaka factors?

A set of four transcription factors (Oct4, Sox2, Klf4, c-Myc) that can reprogram adult cells to a pluripotent state. Partial reprogramming with Yamanaka factors is being explored to reverse cellular aging.

Nicotinamide mononucleotide, a precursor to NAD+ that is widely studied as a supplement to boost cellular energy and combat age-related decline.

A gene-editing technology that allows precise modifications to DNA. In longevity research, CRISPR is used to study and potentially modify genes associated with aging.

A cellular housekeeping process where cells break down and recycle damaged components. Declines with age and is stimulated by fasting.

What is Intermittent fasting?

An eating pattern that cycles between periods of fasting and eating. Various protocols (16:8, 5:2) are studied for metabolic, cardiovascular, and longevity benefits.

What is Zone 2 cardio?

Low-intensity aerobic exercise performed at roughly 60–70% of maximum heart rate, primarily using the aerobic energy system. Associated with mitochondrial health and longevity.

Geographic regions identified by researchers where people consistently live longer and healthier lives than average, including Sardinia, Okinawa, and Loma Linda.

New Treatments for Skin Conditions on the Horizon

Verrica Pharmaceuticals has announced that its CEO, Jayson Rieger, will present at the H.C. Wainwright 4th Annual BioConnect Investor Conference on May 19, 2026. This event, held at NASDAQ, will provide insights into Verrica’s innovative treatments for skin diseases, including skin cancers. You can watch the presentation live online or access a recorded version for 90 days afterward.

Verrica is focused on developing medications for dermatological conditions, particularly skin cancers and infections. One of their key products, YCANTH® (VP-102), is the first FDA-approved treatment for molluscum contagiosum, a contagious viral skin infection that affects around 6 million people in the U.S., mostly children. This treatment offers a new option for families dealing with this common skin issue. Additionally, Verrica is working on solutions for common warts, which remain a significant unmet need in dermatology.

The company is also collaborating with Lytix Biopharma to advance VP-315, a treatment for non-melanoma skin cancers like basal cell carcinoma and squamous cell carcinoma. While these developments are promising, they are still in the early stages of commercialization. As such, it’s important to stay informed about these advancements, especially if you or someone you know is affected by these skin conditions.

If you’re interested in skin health and potential new treatments, keep an eye on Verrica’s progress and consider discussing these options with your healthcare provider.

Source: globenewswire.com